Presentation: Advances in Progressive MS

Peter A. Calabresi, MD
Director, Division of Neuroimmunology
Professor of Neurology
Johns Hopkins University Medical Center
Baltimore, MD


Learning Objectives

After viewing this presentation, the participant should be able to:
  • Review pathophysiology of progressive MS
  • Identify recent advances in imaging markers of leptomeningeal Inflammation
  • Summarize research targeting glial-mediated mechanisms of neurodegeneration
  • Postulate reasons why endogenous remyelination fails


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Intended Audience

Neurologists and neuroscience nurses, as well as other clinicians practicing in MS comprehensive care centers, freestanding MS centers, private and group practices, MS academic and research programs, rehabilitation centers, VA MS COE programs, and long-term care facilities.
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Requirements for Successful Completion

To successfully complete this activity for CE credit, the participant will:
1. Take the pretest
2. Review the content in the presentation
3. Complete the posttest with a score of at least 3 correct answers
4. Fill out a brief evaluation


Upon completion of the requirements 1 – 4, a CME or CE certificate will be available for download.


Release & Expiration Dates
December 1, 2019 to November 30, 2020


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Disclosure Information and Off-Label Uses
It is the policy of Letters & Sciences and the Postgraduate Institute for Medicine to ensure balance, independence, objectivity, and scientific rigor in all their sponsored educational activities. All faculty participating in this activity are expected to disclose to the learners any real or perceived conflicts of interest related to the content of their presentations.

It is not assumed that these financial interests or affiliations will have an adverse impact on the faculty presentations. They simply are noted here to fully inform participants.


Marijean A. Buhse, PhD, RN, ANP-BC, MSCN, FAAN
  • Has served as consultant for: Biogen
  • Has served on the speaker’s bureau: Biogen, Sanofi Genzyme

Peter A. Calabresi, MD
  • Has served as a consultant for: Biogen
  • Has served on the Scientific Advisory Board for: Disarm Therapeutics
  • Has received research grants from: Annexon, Biogen

Rebecca S. Farber, MD
  • Has no real or apparent conflict of interest to report

Mark S. Freedman, MSc, MD, FANA, FAAN, FRCPC
  • Has received honoraria or consultation fees from: Janssen (J&J/Actelion), Alexion, BiogenIdec, Celgene (BMS), Chugai, EMD Inc. (Canada), EMD Serono, Hoffman La-Roche, Novartis, Sanofi-Genzyme
  • Has served as member of a company advisory board, scientific advisory board, board of directors or other similar group: Janssen (J&J/Actelion), Alexion, Bayer Healthcare, BiogenIdec, Clene Nanomedicine, Chugai, EMD Serono, Hoffman La-Roche, MedDay, Novartis, Sanofi-Genzyme
  • Has received research or educational grants from: Sanofi-Genzyme Canada
  • Has participation in a company sponsored speaker’s bureau: Sanofi-Genzyme, EMD Serono

Jonathan E. Howard, MD
  • Has no real or apparent conflict of interest to report

Claire S. Riley, MD
  • Has served as consultant for: Biogen, Celgene, EMD Serono, Genentech, Roche, Sanofi Genzyme
  • Has received research grant from: Biogen

Carrie Lyn Sammarco, DrNP, FNP-C, MSCN
  • Has served on the speaker’s bureau for: Biogen, Genentech, Sanofi Genzyme

Executive Committee, CME/CNE Committees, Curriculum Committee Members
Letters & Sciences and the Postgraduate Institute for Medicine, as accredited providers, content managers/ members of the executive and curriculum committees, report no relationships with commercial interests.

External Review
Letters & Sciences, in compliance with the standards of ANCC, and the Postgraduate Institute for Medicine, in compliance with the standards of the ACCME to identify and resolve any potential conflicts of interest, to assure fair balance, independence and objectivity, and to instill scientific rigor in all accredited activities, report that all presentations with any potential for conflicts of interest, have been reviewed by external reviewers. The external reviewers, who have no potential conflicts of interest, have determined that no bias exists in these presentations. The external reviewers are:

Shannon L. DeVita, MSN, RN, CNL, DNP
University of San Diego
San Diego, California

Michele Nichols, PharmD
Pharmacy Consultant
Private Practice
Raritan, New Jersey
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Accreditation Statements
Joint Acreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine (PIM) and Letters & Sciences. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

Physician Continuing Medical Education
The Postgraduate Institute for Medicine designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)®. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

To receive acknowledgement for participating in this activity, learners must complete the evaluation form.

Continuing Nursing Education
Letters & Sciences is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Each activity has been designated for 0.5 contact hours.

Nonendorsement of Products
The participant is advised that the educational content contained herein was developed by and reflects the opinions of the presenters and faculty, and does not necessarily reflect the opinions or recommendations of the educational provider or the commercial supporter. Accredited status does not imply endorsement by Letters & Sciences or the American Nurses Credentialing Center’s Commission on Accreditation of any commercial product discussed/displayed in conjunction with the educational activity.

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Commercial Support

This program is supported by an educational grant from EMD Serono.
EMD Serono Inc. is an affiliate of Merck KGaA, Darmstadt, Germany.


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