Presentation:  Immunologic Mechanisms for MS: Overview of Evidence & Potential Targets for Treatment
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1. Which of the following is evidence that MS is a primary disorder of immune dysregulation?

a. T and B cells are found within demyelinating lesions

b. CNS-antigen specific immune responses in MS patients

c. Disease responds to treatment with immune modulation

d. Immunologically relevant genes

e. All of the above

2. Which of the following is not a pathogenic role of microglia/macrophages in MS?

a. Anti-inflammatory

b. Cytokine secretion

c. Mediates myelin destruction